1 resultado para PHYLOGENETIC LINEAGES
em WestminsterResearch - UK
Filtro por publicador
- Aberdeen University (3)
- Aberystwyth University Repository - Reino Unido (1)
- Acceda, el repositorio institucional de la Universidad de Las Palmas de Gran Canaria. España (1)
- AMS Tesi di Dottorato - Alm@DL - Università di Bologna (6)
- Aquatic Commons (1)
- ArchiMeD - Elektronische Publikationen der Universität Mainz - Alemanha (7)
- Archimer: Archive de l'Institut francais de recherche pour l'exploitation de la mer (1)
- Archivo Digital para la Docencia y la Investigación - Repositorio Institucional de la Universidad del País Vasco (2)
- Aston University Research Archive (1)
- Biblioteca de Teses e Dissertações da USP (2)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (47)
- Biblioteca Digital da Produção Intelectual da Universidade de São Paulo (BDPI/USP) (49)
- Biblioteca Digital de Teses e Dissertações Eletrônicas da UERJ (2)
- Biodiversity Heritage Library, United States (5)
- Bioline International (2)
- BORIS: Bern Open Repository and Information System - Berna - Suiça (52)
- Brock University, Canada (7)
- Bucknell University Digital Commons - Pensilvania - USA (2)
- CaltechTHESIS (1)
- CentAUR: Central Archive University of Reading - UK (48)
- Chinese Academy of Sciences Institutional Repositories Grid Portal (161)
- Cochin University of Science & Technology (CUSAT), India (4)
- CORA - Cork Open Research Archive - University College Cork - Ireland (1)
- Deakin Research Online - Australia (33)
- Digital Commons - Michigan Tech (1)
- Digital Commons at Florida International University (8)
- DigitalCommons - The University of Maine Research (1)
- DigitalCommons@The Texas Medical Center (5)
- DigitalCommons@University of Nebraska - Lincoln (2)
- DRUM (Digital Repository at the University of Maryland) (2)
- Duke University (12)
- eResearch Archive - Queensland Department of Agriculture; Fisheries and Forestry (14)
- FUNDAJ - Fundação Joaquim Nabuco (1)
- Helda - Digital Repository of University of Helsinki (15)
- Indian Institute of Science - Bangalore - Índia (15)
- INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES (IPEN) - Repositório Digital da Produção Técnico Científica - BibliotecaTerezine Arantes Ferra (1)
- National Center for Biotechnology Information - NCBI (63)
- Plymouth Marine Science Electronic Archive (PlyMSEA) (10)
- Publishing Network for Geoscientific & Environmental Data (10)
- QUB Research Portal - Research Directory and Institutional Repository for Queen's University Belfast (28)
- Queensland University of Technology - ePrints Archive (54)
- Repositório Alice (Acesso Livre à Informação Científica da Embrapa / Repository Open Access to Scientific Information from Embrapa) (1)
- Repositório Científico da Universidade de Évora - Portugal (3)
- Repositório Digital da UNIVERSIDADE DA MADEIRA - Portugal (2)
- Repositório Institucional da Universidade de Aveiro - Portugal (1)
- Repositório Institucional da Universidade de Brasília (2)
- Repositorio Institucional de la Universidad de Málaga (1)
- Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho" (159)
- SAPIENTIA - Universidade do Algarve - Portugal (2)
- School of Medicine, Washington University, United States (1)
- Universidad de Alicante (1)
- Universidad del Rosario, Colombia (2)
- Universidad Politécnica de Madrid (7)
- Universidade Complutense de Madrid (1)
- Universidade de Lisboa - Repositório Aberto (2)
- Universidade de Madeira (1)
- Universidade Estadual Paulista "Júlio de Mesquita Filho" (UNESP) (1)
- Universidade Federal do Pará (16)
- Universidade Federal do Rio Grande do Norte (UFRN) (1)
- Universitat de Girona, Spain (1)
- Universitätsbibliothek Kassel, Universität Kassel, Germany (1)
- Université de Lausanne, Switzerland (5)
- Université de Montréal (2)
- Université de Montréal, Canada (9)
- University of Canberra Research Repository - Australia (2)
- University of Connecticut - USA (3)
- University of Michigan (1)
- University of Queensland eSpace - Australia (33)
- University of Washington (1)
- WestminsterResearch - UK (1)
Resumo:
SELECTOR is a software package for studying the evolution of multiallelic genes under balancing or positive selection while simulating complex evolutionary scenarios that integrate demographic growth and migration in a spatially explicit population framework. Parameters can be varied both in space and time to account for geographical, environmental, and cultural heterogeneity. SELECTOR can be used within an approximate Bayesian computation estimation framework. We first describe the principles of SELECTOR and validate the algorithms by comparing its outputs for simple models with theoretical expectations. Then, we show how it can be used to investigate genetic differentiation of loci under balancing selection in interconnected demes with spatially heterogeneous gene flow. We identify situations in which balancing selection reduces genetic differentiation between population groups compared with neutrality and explain conflicting outcomes observed for human leukocyte antigen loci. These results and three previously published applications demonstrate that SELECTOR is efficient and robust for building insight into human settlement history and evolution.